CAS:1876467-74-1|BAY-1895344

Catalogue Number:B118925
Chemical Name:BAY-1895344
Synonyms:(R)-3-Methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine; 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridine
CAS Number:1876467-74-1
Molecular Formula:C₂₀H₂₁N₇O
Appearance:Orange Solid
Melting Point:>200°C (dec.)
Molecular Weight:375.43
Storage:-20°C, Hygroscopic
Solubility:Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor used in the treatment of advanced hyperproliferative disease, prophylaxis, solid tumors and lymphomas.
References:Wortmann, L., et al.: From PCT Int. Appl. (2016), WO 2016020320 A1 20160211
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