CAS:222631-44-9|BCX 4430

CAS:222631-44-9|BCX 4430

Catalogue Number:B119190
Chemical Name:BCX 4430
Synonyms:(2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol Monohydrochloride; (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol Hydrochloride
CAS Number:222631-44-9
Alternate CAS #
249503-25-1 free amine
Molecular Formula:C₁₁H₁₆ClN₅O₃
Molecular Weight:301.73
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BCX 4430 is an antiviral drug, an adenosine analog). It is developed by BioCryst Pharmaceuticals with funding from NIAID, originally intended as a treatment for Hepatitis C, but subsequently developed as a potential treatment for deadly filovirus infections such as Ebola virus disease and Marburg virus disease.
References:Warren, T., et al.: Nature, 508, 7496 (2014); Kamat, S., et al.: Biochem., 52, 7366 (2013)
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