CAS:252979-56-9|Banoxantrone Dihydrochloride

Catalogue Number:B129285
Chemical Name:Banoxantrone Dihydrochloride
Synonyms:1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione Dihydrochloride
CAS Number:252979-56-9
Molecular Formula:C₂₂H₂₈N₄O₆ • 2(HCl)
Molecular Weight:517.4
Category:Standards; Enzyme Activators and Inhibitors;
Applications:Banoxantrone (AQ4N) is a hypoxia-activated prodrug of topoisomerase II inhibitor AQ4 (Bioreductive AQ4 precursor). studies have shown that its has also exhibited anti-tumor efficacy in vivo when combined with oxic cell cytotoxins.
References:Lalani, A. S. et al.: Clinical cancer research,13(13), undefined (2007-4-4); Nesbitt H. et al.: Clinical cancer research, 23(23), undefined (2016-10-5);
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