CAS:414864-00-9|Belinostat(PXD-101)

Catalogue Number:B131400
Chemical Name:Belinostat(PXD-101)
Synonyms:N-Hydroxy-3-(3-phenylsulfamoylphenyl)acrylamide; PX 105684; PXD 101; PXD-101
CAS Number:414864-00-9
Alternate CAS #
E-conformer 866323-14-0
Molecular Formula:C₁₅H₁₄N₂O₄S
Appearance:Off-White to Pale Orange Solid
Melting Point:142 – 145°C
Molecular Weight:318.35
Storage:4°C, Inert atmosphere, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Light Sensitive
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Belinostat is a novel histone deacetylase 3 selective inhibitor, which protects the b cells from cytokine-induced apoptosis.
References:Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);
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