CAS:178554-16-0|2-Butyl-1,6-dihydro-4-methyl-6-oxo-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-5-pyrimidineacetic Acid

Catalogue Number:B175540
Chemical Name:2-Butyl-1,6-dihydro-4-methyl-6-oxo-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-5-pyrimidineacetic Acid
CAS Number:178554-16-0
Molecular Formula:C₂₅H₂₆N₆O₃
Molecular Weight:458.51
Category:Standards; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Boiling Point
717.0±70.0 °C
Applications:2-Butyl-1,6-dihydro-4-methyl-6-oxo-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-5-pyrimidineacetic Acid can be used for the characterization of metabolites in human liver microsomes and plasma using quantitative and qualitative analysis. It can also be used for synthesis and antagonists for angiotensin II receptor type 1 (AT1) and for anti-hypertensive activity of pyrimidin-4(3H)-one losartan analogs.
References:Lee, J.Y., et.al., Xenobiotica, 46,40-51,(2016); Kim, T.W., et.al., Bioorganic Med.Chem.Lett., 22,1649-1654,(2012);
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