4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide

Chemical Name:4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide
Synonyms:D 4476
CAS Number:301836-43-1
Molecular Formula:C₂₃H₁₈N₄O₃
Molecular Weight:398.41
Category:Research Tools;
Applications:4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide is a novel CK1 inhibitor that potently inhibits CK1 with an IC50 value of 78 nM.
References:Yang, L.L., et al.: Euro. J. Med. Chem., 56, 30 (2012); Sandow, J.J., et al.: Cell. Death. Diff., 19, 633 (2012); Perez, D. I., et al.: Med. Res. Rev., 31, 924, 2011;
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