CAS:690211-38-2|(2R,5R)-Benzyl 2-(But-3-en-1-yl)-5-(prop-1-yn-1-yl)pyrrolidine-1-carboxylate

Catalogue Number:B275460
Chemical Name:(2R,5R)-Benzyl 2-(But-3-en-1-yl)-5-(prop-1-yn-1-yl)pyrrolidine-1-carboxylate
CAS Number:690211-38-2
Molecular Formula:C₁₉H₂₃NO₂
Molecular Weight:297.39
Category:Building Blocks; Chiral Molecules;
Applications:(2R,5R)-Benzyl 2-(But-3-en-1-yl)-5-(prop-1-yn-1-yl)pyrrolidine-1-carboxylate is an intermediate in the synthesis of (+)-Anatoxin A Hydrochloride (A653360), a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.
References:Ueno, Y., et al.: Carcinogenesis, 17, 1317 (1996); Yu, F., et al.: J. Agric Food Chem., 50, 4176 (2002); Welker, M., et al.: Environ. Toxicol., 17, 367 (2002); Furey, A., et al.: Toxicon, 41, 297 (2003);
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