CAS:1638499-31-6|(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine

Catalogue Number:B276215
Chemical Name:(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Synonyms:Tofacitinib Impurity 62; (3R,​4S)​-N,​4-Ddimethyl-​1-​(phenylmethyl)​-3-​piperidinamine
Impurity:Tofacitinib
CAS Number:1638499-31-6
Molecular Formula:C₁₄H₂₂N₂
Molecular Weight:218.34
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
References:Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)
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