CAS:5262-10-2|(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid

Catalogue Number:B276305
Chemical Name:(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid
Synonyms:(2S,5S)-3,6-Dioxo-5-(phenylmethyl)-2-piperazineacetic Acid; (2S-cis)-3,6-Dioxo-5-(phenylmethyl)-2-piperazineacetic Acid; Aspartame Related Compound A (USP); Aspartame impurity A (EP); Aspartame EP Impurity A
Impurity:Aspartame EP Impurity A/ Aspartame USP Related Compound A
CAS Number:5262-10-2
Molecular Formula:C₁₃H₁₄N₂O₄
Appearance:White to Off-White Solid
Melting Point:>165°C (dec.)
Molecular Weight:262.26
Storage:4°C
Solubility:Acetic Acid (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Very Sligh
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid (Aspartame EP Impurity A) is the diketopiperazine impurity of the sweetening agent Aspartame (A790015). It is also found in in processed cocoa powder.
References:Ciranni Signoretti, E. et al.: Boll. Chim. Farmac., 122, 289 (1983); Prudel, M. et al.: Nahrung, 29, 381 (1985); Bonvehi, J.S. et al.: Eur. Food. Res. Technol., 210, 189 (2000);
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