3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride

Chemical Name:3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride
Synonyms:3-[(2,7-Dimethoxyacridin-9-yl)thio]propan-1-amine Hydrochloride; LDN-192960 Hydrochloride
CAS Number:184582-62-5
Alternate CAS #:Free Base: 184582-62-5
Molecular Formula:C₁₈H₂₀N₂O₂S
Molecular Weight:328.43
Category:Research Tools;
Applications:3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride, is an acridine analog, acting as haspin and DYRK2 kinase inhibitor. The studies has also shown that they can have antitrypanosomal and antiplasmid properties.
References:Tanaka, M., et al.: Heterocyclic Communications, 2, 463 (1996); Cuny, G. D., et al.: Bioorg. Med. Chem. Lett., 20, 3491 (2010);
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