(2R,5S)-2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one Hydrochloride

Chemical Name:(2R,5S)-2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one Hydrochloride
Molecular Formula:C₁₅H₂₂N₂O • HCl
Molecular Weight:246.35 + 36.46
Category:Standards;
Applications:2R,5S-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one Hydrochloride is the salt analogue of 2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one (D477055), an impurity of Prilocaine (Prilocaine Hydrochloride P725000). Prilocaine is a local anesthetic of the amino amide type and is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA) towards the treatment of conditions like paresthesia.
References:Caliaro, G., et al.: J. Pharm. Biomed. Anal., 26, 427 (2001), Ulmeanu, S., et al.: Pharm. Res., 20, 1317 (2003)
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