O-Ethyl Elagolix Methoxy-d3

Chemical Name:O-Ethyl Elagolix Methoxy-d3
Synonyms:Ethyl 4-[[(1R)-2-[5-[2-Fluoro-3-(methoxy-d3)phenyl]-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-butanoic Ester;
CAS Number:2233595-40-7
Molecular Formula:C₃₄H₃₁D₃F₅N₃O₅
Molecular Weight:662.66
Category:Building Blocks; Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:O-Ethyl Elagolix methoxy-d3 is an intermediate used in the synthesis of Elagolix Methoxy-d3 Sodium Salt (E501024), which is the labeled analogue of Elagolix (E50108), a novel uracil phenylethylamine that acts as potent human gonadotropin-​releasing hormone receptor (hGnRH-​R) antagonist.
References:Chen, C. et al.: J. Med. Chem., 51, 7478 (2008);
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