Chemical Name:Erlotinib-13C6 Hydrochloride
Synonyms:N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine-13C6 Hydrochloride; 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline-13C6 Hydrochloride; [6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine-13C6 HydrochloridCP 358774-13C6; OSI 774-13C6; Tarceva-13C6;
Alternate CAS #:183319-69-9
Molecular Formula:C₁₆¹³C₆H₂₃N₃O₄ • HCl
Appearance:White to Off-White Solid
Melting Point:221 – 223°C
Molecular Weight:399.39 +(36.46)
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Erlotinib-13C6 Hydrochloride, is the labeled analogue of Erlotinib Hydrochloride (E625000), a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.
References:Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001), Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004), Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005),
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Erlotinib-13C6 Hydrochloride
