20(R)-Ginsenoside Rg3-d6

Chemical Name:20(R)-Ginsenoside Rg3-d6
Synonyms:(3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside-d6; (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside-d6; 20(R)-Propanaxadiol-d6; 20R-Ginsenoside Rg3-d6; R-Ginsenoside Rg3-d6
Alternate CAS #:Unlabelled: 38243-03-7
Molecular Formula:C₄₂H₆₆D₆O₁₃
Molecular Weight:791.05
Category:Standards; Isotopic Labeled Analogues;
Applications:20(R)-Ginsenoside Rg3-d6 is the labelled version of 20(R)-Ginsenoside Rg3, which causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated, relating to in vivo inhibition of tumor angiogenesis of lung cancer.
References:Liu, Y., et al.: Chengdu Yixueyuan Xuebao, 9, 4 (2014); Liu, Y., et al.: Linchuang Junyi Zazhi, 42, 1138 (2014), Kim, D., et al.: Toxicol. Lett., 259, 1 92016); Geng, L., et al.: Zhonghua Zhongyiyao Zazhi, 29, 601 (2014)
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