Hydroxymethyl Ruxolitinib

Chemical Name:Hydroxymethyl Ruxolitinib
Synonyms:3-Cyclopentyl-3-(4-(5-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-imidazol-1-yl)propanenitrile
Molecular Formula:C₁₈H₂₀N₆O
Molecular Weight:336.39
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Hydroxymethyl Ruxolitinib is an impurity of Ruxolitinib. Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
References:Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);
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