2-[4-(1-Hydroxyoctyl)phenyl]ethyl Acetate

Chemical Name:2-[4-(1-Hydroxyoctyl)phenyl]ethyl Acetate
Synonyms:4-(1-Hydroxyoctyl)phenethyl Acetate
Molecular Formula:C₁₈H₂₈O₃
Molecular Weight:292.41
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-[4-(1-Hydroxyoctyl)phenyl]ethyl Acetate is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.
References:Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004)
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