4-Hydroy PAC-1

Chemical Name:4-Hydroy PAC-1
Synonyms:(E)-N’-(3-Allyl-2,4-dihydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide
Molecular Formula:C₂₃H₂₈N₄O₃
Molecular Weight:408.49
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Hydroy PAC-1 is a related compound of PAC-1 (P132000), which is a synthetic compound that activates caspase 3 and induces apoptosis. PAC-1 exhibits anti-tumor properties.
References:Slee, E., et al.: J. Biol. Chem., 276, 7320 (2001), Pop, C., et al.: Biochemistry, 42, 12311 (2003), Li, L., et al.: Science, 305, 1471 (2004), Green, D., et al.: J. Clin. Invest., 115, 2610 (2005), Satoh, T., et al.: Clin. Cancer Res., 15, 3872 (2009)
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