Indacaterol 8-O-Glucuronide

Indacaterol 8-O-Glucuronide

Chemical Name:Indacaterol 8-O-Glucuronide
Synonyms:(2S,3S,4S,5R)-6-((5-((R)-2-((5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-2-oxo-1,2-dihydroquinolin-8-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
CAS Number:1446354-20-6
Molecular Formula:C₃₀H₃₆N₂O₉
Molecular Weight:568.61
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Indacaterol 8-O-Glucuronide is an impurity of Indacaterol (I499745), a β-adrenoreceptor agonists for treatment of asthma and bronchodilator treatment for patients with chronic obstructive pulmonary diseases.
References:Crisafulli, E., et al.; Expert Opinion Pharmacother., 18, 1499 (2017); Aparici, M., et al.: Pul. Pharmacol. Ther., 46, 1 (2017); Demin, I., et al.: Int. J. Clin. Pharmacol. Ther., 54, 405 (2016)
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