rac-Isotimolol

Chemical Name:rac-Isotimolol
Synonyms:3-[(1,1-Dimethylethyl)amino]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-1-propanol; 1,2,5-Thiadiazole 1-Propanol derivative; Timolol EP Impurity B; Timolol BP Impurity B; Timolol USP Related Compound B
Impurity
Timolol EP Impurity B; Timolol BP Impurity B; Timolol USP Related Compound B
CAS Number:59697-06-2
Molecular Formula:C₁₃H₂₄N₄O₃S
Molecular Weight:316.42
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:rac-Isotimolol (Timolol EP Impurity B; Timolol BP Impurity B; Timolol USP Related Compound B) is an analog of Timolol (T443700); an antihypertensive, antiarrhythmic (class II), antianginal, and antiglaucoma agent.
References:Wasson, et al.: J. Med. Chem., 15, 651 (1972); Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972); Heel, R.C., et al.: Drugs, 17, 38 (1979); Rofman, B.A., et al.: Hypertension, 2, 643 (1980); Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987); Sharma, N., et al.: J. Chromatogr. Sci., 50, 745 (2012)
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