2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-[(6-chloro-2-methoxy-9-acridinyl)amino]-1-hexanol

Chemical Name:2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-[(6-chloro-2-methoxy-9-acridinyl)amino]-1-hexanol
CAS Number:147190-46-3
Alternate CAS #:157774-65-7
Molecular Formula:C₄₂H₄₃ClN₂O₅
Molecular Weight:691.25
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-[(6-chloro-2-methoxy-9-acridinyl)amino]-1-hexanol is an impurity of 6-Amino-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)hexan-1-ol (A489205), which is a derivative of 1-O-Dimethoxytrityl-2-(N-Fmoc)-4-Aminobutyl)-1,3-propanediol (D460760) a useful reagent for the synthesis of acridine and​/or lipid containing oligodeoxyribonucleotides. It can be prepared using cross-coupling reaction and amidation, and to to study host-guest inclusion in hybyridization. This compound is a C7 linker derivative.
References:Kuzuya, A., et.al.: Bioconjugate Chemistry, 20, 1643-1649, (2009); Marasco, C. J., et al.: Tetra. Lett., 35, 3029 (1994);
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