5-​Amino-​N-​[4-​[bis(5-​amino-​2-​methylphenyl)​methyl]​phenyl]​-​2-​methylbenzenesulfonamide

Chemical Name:5-​Amino-​N-​[4-​[bis(5-​amino-​2-​methylphenyl)​methyl]​phenyl]​-​2-​methylbenzenesulfonamide
CAS Number:1226500-00-0
Molecular Formula:C₂₈H₃₀N₄O₂S
Molecular Weight:486.63
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-​Amino-​N-​[4-​[bis(5-​amino-​2-​methylphenyl)​methyl]​phenyl]​-​2-​methylbenzenesulfonamide is a impurity of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References:Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009),
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