EIDD 1931-13C5 (N4-Hydroxycytidine-13C5)

Chemical Name:EIDD 1931-13C5 (N4-Hydroxycytidine-13C5)
Synonyms:(Z)-1-((2R,3R,4S,5R)-3,4Dihydroxy-5-(hydroxymethyl-13C)tetrahydrofuran-2-yl-2,3,4,5-13C4)-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1H)-one; EIDD 2166;
CAS Number:1955549-11-7
Molecular Formula:C₄H₁₃C₅H₁₃N₃O₆
Molecular Weight:264.18
Applications:Isotope labelled EIDD 1931 is an orally bioavailable broad-spectrum anti-viral that inhibits SARS-CoV-2 and other multiple endemic, epidemic and bat coronavirus and has the potential for seasonal and pandemic influenza treatment. A broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses.
References:Sheahan, T. P., et al.: Sci. Transl. Med., 12, eabb5883 (2020); Agostini, M. L., et al.: J. Virol., 93, 01348 (2019); Yoon, J., et al.: Antimicrob. Agents and Chemother., 62, 00766 (2018); Barnard, D. L., et al.: Antivir. Chem. Chemother., 17, 275 (2006)
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