Chemical Name:2-Fluoro-3-nitro-N-[4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2-(trifluoromethyl)phenyl]-benzamide
CAS Number:2416320-48-2
Molecular Formula:C₁₇H₇F₁₁N₂O₃
Molecular Weight:496.23
Category:Building Blocks;
Applications:2-Fluoro-3-nitro-N-[4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2-(trifluoromethyl)phenyl]-benzamide is an intermediate in the synthesis of Broflanilide (B677570), a pesticide for controlling animals and microbial pests such as unwanted insects. Broflanilide is a prominent insecticide because of it’s effective against pests with resistance to cyclodienes and fipronil. Broflanilide is metabolized to desmethyl-broflanilide that acts as a noncompetitive resistant-to-dieldrin (RDL) γ-aminobutyric acid (GABA) receptor antagonist.
References:An, X., et al.: J. Sep. Sci., 41, 4515 (2018); Zhao, P., et al.: Nongyao Kexue Yu Guanli, 36, 23 (2015); Jeanmart, S., et al.: Bioorg. Med. Chem., 24, 317 (2016); Nakao, T., et al.: Bioorg. Med. Chem., 24, 372 (2016)
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2-Fluoro-3-nitro-N-[4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2-(trifluoromethyl)phenyl]-benzamide
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