N-Formyl Axitinib

N-Formyl Axitinib

Chemical Name:N-Formyl Axitinib
Synonyms:N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-[N-formyl, 1H-indazol-6-yl-thio]] -benzamide; (E)-2-((1-formyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide
Molecular Formula:C₂₃H₁₈N₄O₂S
Molecular Weight:414.48
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Formyl Axitinib is an impurity of Axitinib (A794650), a tyrosine kinase inhibitor used in cancer therapy.
References:Wasser, K., et al.: Eur. Radiol., 13, 80 (2003); Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002); Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003);
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