GW 441756-D₃

Chemical Name:GW 441756-D₃
Synonyms:(Z)-3-((1-(methyl-d3)-1H-indol-3-yl)methylene)-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one
Alternate CAS #:504433-23-2
Molecular Formula:C₁₇H₁₀D₃N₃O
Molecular Weight:278.33
Category:Standards; Isotopic Labeled Analogues; Molecular Biology; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:GW 441756-D₃ is a labelled analog of GW 441756 (CAS# 504433-23-2), which is an effective Trk binder, a novel bioactive molecule used in the treatment of neuroblastoma in infants.
References:Leitao, A. et al.: Chem. Bio. Drug Design., 82, 233 (2013); Wood, E. et al.: Bioorg. Med. Chem. Lett., 14, 953 (2004)
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