2-Hydroxy-3-methyl-butanedioic Acid

Chemical Name:2-Hydroxy-3-methyl-butanedioic Acid
Synonyms:3-Methylmalic Acid; β-Methylmalic Acid;
CAS Number:608-41-3
Molecular Formula:C₅H₈O₅
Molecular Weight:148.11
Category:Building Blocks; Amino Acids;
Applications:2-Hydroxy-3-methyl-butanedioic Acid is used as a sole C source when metabolized by soil bacterium; Also, it is an intermediate used in the synthesis of 5-Methyl-2’-deoxy Cytidine-13C,15N2 (M295904), which is an isotopic analog of 5-Methyl-2’-deoxy Cytidine (M295900), a Cytidine (C998300) analog and also an isostere of Thymidine (T412000).
References:Nakano, H., et al.: J. Biochem., 70, 429-440 (1971); Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008)
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