5-Hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-7-pentyl-2H-1-benzopyran-6-carboxaldehyde

Chemical Name:5-Hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-7-pentyl-2H-1-benzopyran-6-carboxaldehyde
Synonyms:5-Hydroxy-2-methyl-2-(4-methylpent-3-en-1-yl)-7-pentyl-2H-chromene-6-carbaldehyde
CAS Number:882429-52-9
Molecular Formula:C₂₂H₃₀O₃
Appearance:Orange/Red Oil
Molecular Weight:342.47
Storage:-20°C
Solubility:Chloroform; Dichloromethane; DMSO; Ethyl Acetate; Methanol
Category:Building Blocks; Miscellaneous;
Applications:5-Hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-7-pentyl-2H-1-benzopyran-6-carboxaldehyde is an intermediate in the synthesis of (±)-Cannabichromenic Acid (C175285), which is a derivative of (±)-Cannabichromene (C175280), which is a non Δ9-tetrahydrocannabinol (THC) phytocannabinoid, that increases viability and inhibits differentiation into astroglia through upregulation of ATP and adenosine signaling in adult mouse neural stem progenitor cells (NSPC). (±)-Cannabichromene is a potent rat transient receptor potential (TRP)A1 agonist and desensitizer.
References:Shinjyo, N., Di Marzo, V.: Neurochem. Int., 63, 432 (2013); De Petrocellis, L., et. al.: Brit. J. Pharmacol., 163, 1479 (2011)
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