N-​(4-​(2-​Hydroxy-​3-​(isopropylamino)​propoxy)​phenyl)​butyramide Hydrochloride

Chemical Name:N-​(4-​(2-​Hydroxy-​3-​(isopropylamino)​propoxy)​phenyl)​butyramide Hydrochloride
Synonyms:Acebutolol EP Impurity E Hydrochloride;
Impurity
Acebutolol EP Impurity E
CAS Number:1432053-72-9
Alternate CAS #:Free Base: 27783-53-5
Molecular Formula:C₁₆H₂₆N₂O₃ • HCl
Molecular Weight:294.39 + (36.46)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-​(4-​(2-​Hydroxy-​3-​(isopropylamino)​propoxy)​phenyl)​butyramide Hydrochloride is an impurity of Acebutolol (A123800), a cardioselective β-adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II). (Acebutolol EP Impurity E)
References:Cuthbert, O.A., et al.: Br. J. Pharmacol., 43, 639 (1971), Singh, B.N., et al.: Drugs, 29, 531 (1985), Foster, R.T., et al.: Anal. Profiles Drug Subs., 19, 1 (1990),
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