CAS:74713-59-0|C8 Ceramide

Catalogue Number:C262700
Chemical Name:C8 Ceramide
Synonyms:N-Octanoylsphingosine; N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]octanamide; [R-[R*,S*-(E)]]-N-[2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]octanamide; D-erythro-N-Octanoylsphingosine; N-Octanoyl-C18-sphingosine; N-Octanoyl-D-erythro-sphingosine; N-Octanoylsphingosine;
CAS Number:74713-59-0
Alternate CAS #
175892-44-1
Molecular Formula:C₂₆H₅₁NO₃
Appearance:White to Off-White Solid
Melting Point:68-70°C
Molecular Weight:425.69
Storage:-20°C
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
Category:Standards; Enzyme Activators and Inhibitors; Lipids/Fatty Acids, Glycerol Derivatives;
Applications:A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis.
References:Mathias, S., et al.: Proc. Natl. Sci. USA, 88, 10009 (1991), Mathias, S., et al.: Science, 259, 519 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994)
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