CAS:227947-06-0|3-[4-[1-[4-(3-Chloro-2-hydroxypropoxy)phenyl]-1-methylethyl]phenoxy]-1,2-propanediol

Catalogue Number:C315250
Chemical Name:3-[4-[1-[4-(3-Chloro-2-hydroxypropoxy)phenyl]-1-methylethyl]phenoxy]-1,2-propanediol
Synonyms:EPI 001
CAS Number:227947-06-0
Molecular Formula:C₂₁H₂₇ClO₅
Appearance:Colourless to Off-White Oil to Solid
Molecular Weight:394.89
Storage:4°C
Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator that inhibits androgen receptor expression and activity in prostate cancer. It is a novel androgen receptor antagonists that has the potential for treating prostate cancer.
References:De Mol, E., et a.: ACS Chem Biol. 11, 2499 (2016); Brand, L. J., et al.: Oncotarget. 6, 3811 (2015)
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