CAS:7384-89-6|L-erythro-Chloramphenicol

Catalogue Number:C325015
Chemical Name:L-erythro-Chloramphenicol
Synonyms:[R-(R*,S*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide; L-erythro-(+)-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-acetamide; L-(+)-erythro-Chloramphenicol; L-erythro-(1R,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol; L-erythro-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide
CAS Number:7384-89-6
Molecular Formula:C₁₁H₁₂Cl₂N₂O₅
Appearance:White to Off-White Solid
Melting Point:173-175°C
Molecular Weight:323.13
Storage:-20°C
Solubility:DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Research Tools; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:L-erythro-Chloramphenicol functions as a potent inhibitor of electron transport in the mitochondria in biological studies. The L-isomer can be identified from the other CAP-isomers through reversed phase and chiral liquid chromatography in combination with tandem mass spectrometric detection.
References:Berendsen, B., et al.: Anal. Chim. Acta., 700, 78 (2011), Wilson, S.B., et al.: Biochim. Biophys. Acta., 292, 603 (1973)
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