CAS:26189-59-3|1-Chloro-N,N-2-trimethylpropenylamine (>90%)

Catalogue Number:C349260
Chemical Name:1-Chloro-N,N-2-trimethylpropenylamine (>90%)
Synonyms:1-Chloro-N,N,2-trimethyl-1-propen-1-amine; (1-Chloro-2-methylprop-1-en-1-yl)dimethylamine; (1-Chloro-2-methylpropenyl)dimethylamine;
CAS Number:26189-59-3
Molecular Formula:C₆H₁₂ClN
Appearance:Colourless Oil
Molecular Weight:133.62
Storage:4°C
Solubility:Chloroform (Sparingly), Methanol (Slightly)
Stability
Hygroscopic, Moisture Sensitive, Unstable in Solution
Category:Building Blocks; Miscellaneous;
Applications:1-Chloro-N,N-2-trimethylpropenylamine (>90%) acts as a reagent in the synthesis and antitumor activity of (-)-bassianolide in human cancer cells through cell cycle arrest. Enantioselective total synthesis of nannocystins A and A0 as elongation factor 1 inhibitors. Total synthesis of (-)-caprazamycin A with antibacterial activity against Mycobacterium tuberculosis (TB) via diastereoselective aldol reaction.
References:Mun, B., et al.: Bioorg. Chem., 69, 64 (2016); Huang, J., et al.: Org. Lett., 18, 4702 (2016); Nakamura, H., et al.: Angew. Chem., Int. Ed., 54, 3136 (2015)
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