CAS:539-03-7|4′-Chloroacetanilide

Catalogue Number:C363355
Chemical Name:4′-Chloroacetanilide
Synonyms:N-(4-Chlorophenyl)acetamide; N-(p-Chlorophenyl)acetamide; N-Acetyl-4-chloroaniline; N-Acetyl-p-chloroaniline; p-Chloroacetanilide; NSC 40563; NSC 444; USP Acetaminophen Related Compound J; Paracetamol EP Impurity J
CAS Number:539-03-7
Molecular Formula:C₈H₈ClNO
Appearance:White to Grey Solid
Melting Point:163-165°C
Molecular Weight:169.61
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4′-Chloroacetanilide is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3,4).
References:(1) Călinescu, O., et al.: J. Chromatogr. Sci. 50(4), 335-42, (2012)
(2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)
(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)
(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)
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