CAS:112346-82-4|3-Chloro-D-alanine Methyl Ester Hydrochloride

CAS:112346-82-4|3-Chloro-D-alanine Methyl Ester Hydrochloride

Catalogue Number:C363525
Chemical Name:3-Chloro-D-alanine Methyl Ester Hydrochloride
Synonyms:(S)-Methyl 2-Amino-3-chloropropanoate Hydrochloride; Cycloserine Impurity 3
Impurity:Cycloserine Impurity 3
CAS Number:112346-82-4
Alternate CAS #
Free Base: 327064-64-2
Molecular Formula:C₄H₈ClNO₂•HCl
Appearance:White to Off-White Solid
Melting Point:147 – 149°C
Molecular Weight:137.56+(36.46)
Storage:-20°C, Hygroscopic
Solubility:DMSO (Sonicated), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Chloro-D-alanine Methyl Ester Hydrochloride is an intermediate in the preparation of antibiotic D-Cycloserine (C988815) which inhibits cell wall biosynthesis in bacteria.
References:Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972); Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993); Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994); Auger, S., et al.: Biochimie, 87, 231 (2005); Chem and Eng. News p. 12, Dec. 7/14 (2015);
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