CAS:106-54-7|4-​Chlorothiophenol(4-Chlorobenzenethiol)

CAS:106-54-7|4-​Chlorothiophenol(4-Chlorobenzenethiol)

Catalogue Number:C364595
Chemical Name:4-​Chlorothiophenol(4-Chlorobenzenethiol)
Synonyms:4-Chlorobenzenethiol; p-Chlorobenzenethiol; 1-Chloro-4-mercaptobenzene; 4-Chlorobenzenethiol; 4-Chlorophenylmercaptan; 4-Chlorophenylthiol; 4-Mercaptophenyl chloride; NSC 18714; NSC 229564; p-Chlorobenzenethiol; p-Chlorophenylmercaptan; p-Chlorophenylthiol; p-Chlorothiophenol; p-Mercaptochlorobenzene
CAS Number:106-54-7
Molecular Formula:C₆H₅ClS
Appearance:White to Off-White Low-Melting Solid
Molecular Weight:144.62
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:4-Chlorobenzenethiol is a reagent used in the synthesis of small-molecule inhibitors of the protein geranylgeranyltransferase Type I (GGTase-I), acting as anti-tumor agents. Also is used in the synthesis of b-sulfanyl carbonyl compounds via Michael addition.
References:Ranu, B. et al.: Tetrahedron, 60, 4183 (2004); J. Med. Chem., 43, 2310 (2000);
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