CAS:2468737-75-7|5-Chloro Dasatinib

Catalogue Number:C364925
Chemical Name:5-Chloro Dasatinib
Synonyms:N-​(3,​6-​Dichloro-​2-​methylphenyl)​-​2-​[[6-​[4-​(2-​hydroxyethyl)​-​1-​piperazinyl]​-​2-​methyl-​4-​pyrimidinyl]​amino]​-5-​thiazolecarboxamide;
CAS Number:2468737-75-7
Molecular Formula:C₂₂H₂₅Cl₂N₇O₂S
Appearance:White to Off-White Solid
Melting Point:>196°C (dec.)
Molecular Weight:522.45
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Chloro-dasatinib, is an impurity of Dasatinib (D193600), which is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. It is also an Antineoplastic. It is a COVID19-related research product.
References:Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004), Shah, N. P., et al.: Science, 305, 399 (2004), O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2006),
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