CAS:391860-73-4|6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline

Catalogue Number:C365545
Chemical Name:6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline
Synonyms:2-Cyclopropyl-6-chloro-4-(trifluoromethyl)quinoline, USP Efavirenz Related Compound C
Impurity:Efavirenz USP Related Compound C/ Efavirenz Quinoline Impurity:CAS Number:391860-73-4
Molecular Formula:C₁₃H₉ClF₃N
Appearance:Off-White to Pale Yellow Solid
Melting Point:61-63°C
Molecular Weight:271.67
Storage:4°C
Solubility:Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent.
References:Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995), Jiang, B., et al.: Euro. J. Org. Chem., 16, 2693 (2008); Ribeiro, J.A., et al.: J. Pharma. Biomed. Anal., 43, 298 (2007);
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