CAS:25526-94-7|3′-Chloro-3′-deoxythymidine

Catalogue Number:C365575
Chemical Name:3′-Chloro-3′-deoxythymidine
Synonyms:USP Zidovudine Related Compound B; Zidovudine EP Impurity B;
Impurity:Zidovudine EP Impurity B
CAS Number:25526-94-7
Molecular Formula:C₁₀H₁₃ClN₂O₄
Appearance:White to Off-White Solid
Melting Point:>158°C (dec.)
Molecular Weight:260.67
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3′-Chloro-3′-deoxythymidine (Zidovudine EP Impurity B) is an impurity of 3′-Azido-3′-deoxythymidine (A825000), a potent and selective inhibitor of HIV-1 replication and a potential antiviral agent.
References:Navaneethan, G., et al.: J. Food. Drug Anal., 20, 446 (2012); Srivastav, N.C., et al.: Bioorg. Med. Chem., 18, 7542 (2010); Shakya, N., et al.: J. Med. Chem., 53, 4130 (2010); Fukushima, M., et al.: BIochem. Pharmacol., 59, 1227 (2000);
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