CAS:154026-93-4|(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester (~90%)

Catalogue Number:C365815
Chemical Name:(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester (~90%)
Synonyms:(3R,5S)-6-Chloro-3,5-dihydroxy-,Hexanoic Acid 1,1-dimethylethyl Ester,
CAS Number:154026-93-4
Molecular Formula:C₁₀H₁₉ClO₄
Appearance:Pale Beige to Light Beige Solid
Melting Point:45-49°C
Molecular Weight:238.71
Storage:-20°C
Solubility:Chloroform (Sparingly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester (~90%) is an intermediate in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor.
References:Amidjojo, M., et al.: App. Microbiol. Biotechol., 69, 9 (2005);
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