CAS:1003316-10-6|N-[3-[[4-(Chloromethyl)benzoyl]amino][1,1′-biphenyl]-4-yl]carbamic Acid tert-Butyl Ester

Catalogue Number:C369670
Chemical Name:N-[3-[[4-(Chloromethyl)benzoyl]amino][1,1′-biphenyl]-4-yl]carbamic Acid tert-Butyl Ester
Synonyms:N-[3-[[4-(Chloromethyl)benzoyl]amino][1,1′-biphenyl]-4-yl]carbamic Acid 1,1-Dimethylethyl Ester
CAS Number:1003316-10-6
Molecular Formula:C₂₅H₂₅ClN₂O₃
Appearance:White Solid
Molecular Weight:436.93
Storage:4°C
Solubility:Chloroform, Dichloromethane, Methanol
Category:Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-[3-[[4-(Aminomethyl)benzoyl]amino][1,1′-biphenyl]-4-yl]carbamic Acid tert-Butyl Ester is a reactant used in the preparation of carboxybenzylamino biaryls as histone deacetylase inhibitors and in the optimization of biaryl selective HDAC1&2 inhibitors.
References:Witter, D. et al.: Bioorg. Med. Chem. Lett., 18, 726 (2008)
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