CAS:1431867-40-1|4-Chloro-6-methoxy-2-(propylthio)-5-pyrimidinamine

Catalogue Number:C369935
Chemical Name:4-Chloro-6-methoxy-2-(propylthio)-5-pyrimidinamine
CAS Number:1431867-40-1
Molecular Formula:C₈H₁₂ClN₃OS
Molecular Weight:233.72
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Chloro-6-methoxy-2-(propylthio)-5-pyrimidinamine is an intermediate used in the syntehsis of ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist.
References:Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)
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