CAS:1316847-19-4|2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide

Catalogue Number:C370025
Chemical Name:2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide
Synonyms:2-(4-(4-Chlorobenzoyl)phenoxy)-N-isopropyl-2-methylpropanamide;
CAS Number:1316847-19-4
Molecular Formula:C₂₀H₂₂ClNO₃
Appearance:Beige Solid
Molecular Weight:359.85
Solubility:DCM, Ethyl Acetate, Methanol
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide is an intermediate in synthesizing Fenofibric Acid 1,1-Dimethyl-2-(1-methylethoxy)-2-oxoethyl Ester (F248680), which is an impurity of Febofibrate (F248640). Febofibrate is an antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion.
References:Lacroix, P.M. et al.: J. Pharmac. Biomed. Anal., 18, 383 (1998); Sornay, R., et al.: Arzneim.-Forsch., 26, 885 (1976); Wulfert, W., et al.: Artery, 9, 120 (1981); Chaput, et al.: Lipids, 34, 497 (1999)
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