CAS:889871-36-7|3-Chloro-5-iodo-L-tyrosine

CAS:889871-36-7|3-Chloro-5-iodo-L-tyrosine

Catalogue Number:C370070
Chemical Name:3-Chloro-5-iodo-L-tyrosine
Synonyms:5-Chloro-3-iodo-L-tyrosine; (S)-2-Amino-3-(3-chloro-4-hydroxy-5-iodophenyl)propanoic Acid;
CAS Number:889871-36-7
Molecular Formula:C₉H₉ClINO₃
Appearance:Off-White to Beige Solid
Melting Point:>190°C (dec.)
Molecular Weight:341.53
Storage:4°C
Solubility:DMSO (Slightly), Water (Slightly, Heated, Sonicated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
Applications:3-Chloro-5-iodo-L-Tyrosine is an intermediate in synthesizing 3-Chloro-3’,5,5’-triiodo-L-thyronine , which is a chlorinated derivative of 3,3’,5’-Triiodo-L-thyronine (T795350), used for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.
References:Block, P.: J. Med. Chem., 19(8), 1067-1069 (1976); Shiba, T., & Cahmann, H.J.: J.O.C., 29, 1652-1653 (1964)
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