CAS:5326-23-8|6-Chloronicotinic Acid

Catalogue Number:C370930
Chemical Name:6-Chloronicotinic Acid
Synonyms:6-Chloro-3-pyridinecarboxylic Acid; 2-Chloro-5-pyridinecarboxylic Acid; 3-Carboxy-6-chloropyridine; 6-Chloro-3-pyridinecarboxylic Acid; 6-Chloropyridin-3-carboxylic Acid; NSC 277;
CAS Number:5326-23-8
Molecular Formula:C₆H₄ClNO₂
Appearance:White to Pale Beige Solid
Melting Point:>180°C (dec.)
Molecular Weight:157.55
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:6-Chloronicotinic Acid, is an organic building block used for the synthesis of various biologically active compounds, including inhibitors. It is an intermediate for the synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAFV600E inhibitors, and novel DNA-gyrase B inhibitors.
References:Xie, Y., et al.: Bioorg. Med. Chem. Lett., 23, 2306 (2013); Shiroya, U., et al.: Med. Chem. Res., 22, 5227 (2013);
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