Amgen IRE1α Inhibitor

Chemical Name:Amgen IRE1α Inhibitor
Synonyms:(S)-2-Chloro-N-(6-methyl-5-((3-(2-(piperidin-3-ylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-yl)benzenesulfonamide
CAS Number:1630086-20-2
Molecular Formula:C₃₁H₂₉ClN₆O₃S
Molecular Weight:601.12
Category:Research Tools;
Applications:Amgen IRE1α Inhibitor is an inhibitor of IRE1α. IRE1α is a sensor of unfolded protein accumulation that triggers the unfolded protein response.
References:Harringhton, P.E., et. al.: ACS Med. Chem. Lett., (2014)
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