CAS:1779520-71-6|Alternariol-9-methylether-3-β-D-(6’-malonyl)-glucoside

Catalogue Number:A575960
Chemical Name:Alternariol-9-methylether-3-β-D-(6’-malonyl)-glucoside
Synonyms:3-oxo-3-(((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((7-hydroxy-9-methoxy-1-methyl-6-oxo-6H-benzo[c]chromen-3-yl)oxy)tetrahydro-2H-pyran-2-yl)methoxy)propanoic Acid; 3-[[6-O-(2-Carboxyacetyl)-β-D-glucopyranosyl]oxy]-7-hydroxy-9-methoxy-1-methyl-6H-Dibenzo[b,d]pyran-6-one;
CAS Number:1779520-71-6
Molecular Formula:C₂₄H₂₄O₁₃
Molecular Weight:520.44
Category:Standards; Enzyme Activators and Inhibitors; Environmental Standards, Mutagens and Metabolites;
Applications:Alternariol-9-methylether-3-β-D-(6’-malonyl)-glucoside is a metabolite of Alternariol (A575760), a alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks.
References:Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009), Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009), Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009);
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