Category: Materials

1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)

POPC (1-palmitoyl-2-oleoyl-glycero-3-phosphocholine), a phospholipid with 16:0 and 18:1 acyl chains, can be used for the study of the lipid bilayer properties and other related biophysical experiments with phospholipids. POPC has been considered one of the model lipids for biophysical experiments, and it is also an excellent synthetic substitute for EPC since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC. In addition, POPC can […]

1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)

DOPC (1,2-Dioleoyl-sn-glycero-3-phosphocholine), a kind of phosphatidylcholine (36:2), is a neutral helper phospholipid which can be used in gene and drug delivery liposomal formulations. DOPC has been proven to promote more stable laminar structures. The helper lipids have been shown to improve the transfection efficiency in a variety of cell types when used in combination with charged lipids. At […]

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC)

DMPC (1,2-ditetradecanoyl-sn-glycero-3-phosphocholine) is composed of saturated and symmetric phospholipids with 14 carbon atoms. As a zwitterionic phospholipids, DMPC can be used in the formulation of liposomes, lipid nanoparticles, and other related nanodelivery systems for gene delivery. Also, DMPC can be used for delivery of siRNA, mRNA, and plasmid DNA through the combination with cationic lipids. Furthermore, DMPC can […]

1,2-didodecanoyl-sn-glycero-3-phosphocholine (DLPC)

DLPC (1,2-didodecanoyl-sn-glycero-3-phosphocholine), the dilauroyl diester of phosphatidiylcholine, is one of the most common cell membrane lipids. It can be used as a phospholipid standard to quantify phosphatidylcholine by electrospray ionization mass spectrometry. Properties: Molecular Formula: C32H64NO8P Percent Composition: C 61.81%, H 10.37%, N 2.25%, O 20.58%, P 4.98% Form: White powder Purity: 99% Stability: 2 Years Solubility: 25 […]

1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)

DPPC (1,2-Dipalmitoyl-sn-glycero-3-phosphocholine), an amphipathic phosphocholine with two palmitic acids on its head-group, is used for gene and drug delivery formulations. Due to its excellent biodegradability, drug encapsulation capacity and the high cellular uptake when combined with other lipids, DPPC has become an ideal option for liposomal formulations. As a component of pulmonary surfactants, DPPC can reduce surface tension and is often used in studying bilayers found in human bodies. In […]

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)

DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine) is a phospholtidylcholine with alkyl chain containing 18 carbons. As a a zwitterionic phospholipid, DSPC has been used in the preparation of liposomes for transfection and drug delivery applications. The functions of DSPC are to enhance the encapsulation efficiency and liposome stability which enables greater efficiency in bioprocessing. DSPC has relatively low cytotoxicity and high transfection efficacy. As a […]

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