Drug Delivery

Chemical Name:N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]ethyl]phenyl]formamideCAS Number:1337876-26-2Molecular Formula:C₂₆H₃₀N₂O₄Molecular Weight:434.5Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]ethyl]phenyl]formamide,is an impurity of Arformoterol Tartrate (A767505) which is a long-acting β2 adrenoreceptor agonist (LABA) indicated for the treatment of chronic obstructive pulmonary disease (COPD).References:Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. […]

Chemical Name:Hexanoyl Docetaxel Hydroxy tert-ButylcarbamateSynonyms:(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-2-(hexanoyloxy)-3-((((1-hydroxy-2-methylpropan-2-yl)oxy)carbonyl)amino)-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl BenzoateMolecular Formula:C₄₉H₆₃NO₁₆Molecular Weight:922.02Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Hexanoyl Docetaxel Hydroxy tert-Butylcarbamate is an analogue of Docetaxel Hydroxy tert-Butylcarbamate (D494425), the main metabolite of Docetaxel (D494420), an antineoplastic.References:Commercon, A., et al.: Tetrahedron, 50, 34, 10289 (1994)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee […]

Chemical Name:(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid(Dolutegravir Impurity)Alternate CAS #:4R: 1246616-73-8Molecular Formula:C₁₄H₁₆N₂O₆Molecular Weight:308.29Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid, is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor.References:Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, […]

Chemical Name:(αS,​3aR,​8aS)​-Hexahydro-​2,​2-​dimethyl-​7-​oxo-​α-​[[(phenylmethoxy)​carbonyl]​amino]​-​5H-​1,​3-​dioxolo[4,​5-​c]​azepine-​5-​hexanoic Acid Phenylmethyl EsterSynonyms:(S)-Benzyl 2-(((Benzyloxy)carbonyl)amino)-6-((3aR,8aS)-2,2-dimethyl-7-oxotetrahydro-3aH-[1,3]dioxolo[4,5-c]azepin-5(4H)-yl)hexanoateCAS Number:1820794-38-4Molecular Formula:C₃₀H₃₈N₂O₇Molecular Weight:538.63Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(αS,​3aR,​8aS)​-Hexahydro-​2,​2-​dimethyl-​7-​oxo-​α-​[[(phenylmethoxy)​carbonyl]​amino]​-​5H-​1,​3-​dioxolo[4,​5-​c]​azepine-​5-​hexanoic Acid Phenylmethyl Ester is an intermediate in synthesizing 6R,7S,8aR-Glucosepane Tri-TFA Salt (G595310), one of the eight diastereomers of glucosepane. Glucosepane is a structurally complex protein posttranslational modification that is believed to exist in all living organisms. Research in humans suggests that glucosepane plays […]

Chemical Name:rac-Hesperetin 7-O-Sulfate Sodium Salt-d3Synonyms:(2S)-2,3-Dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(sulfooxy)-4H-1-benzopyran-4-one Sodium SaltAlternate CAS #:Unlabelled: Free Acid: 675139-61-4Molecular Formula:C₁₆H₁₀D₃NaO₉SMolecular Weight:407.34Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;Applications:Hesperetin 7-O-Sulfate Sodium Salt-d3, is the labeled analogue of Hesperetin 7-O-Sulfate Sodium Salt (H289525), which is a metabolite of Hesperidin (H281185), a flavanone glycoside found in citrus fruits, also regarded as Vitamin P.References:Ananth, […]

Chemical Name:Hesperetin-13C,d3Alternate CAS #:520-33-2Molecular Formula:C₁₅¹³CH₁₁D₃O₆Molecular Weight:306.29Category:Standards; Isotopic Labeled Analogues; Natural Products;Applications:Hesperetin 13C-1, D-3 is labelled Hesperetin ( H289500, CAS: 520-33-2) which is a flavanone found in citrus fruits.References:Tsujimoto, M., et al.: Biol. Pharm. Bull., 32, 671 (2009); Wang, H., et al.: J. Pharm. Biomed. Anal., 49, 1157 (2009), Lee, S,. et al.: Bioorg. Med. Chem. […]

Chemical Name:1,​2,​3,​4,​6,​7,​8-​Heptachloro-dibenzofuran-​13C12CAS Number:109719-84-8Alternate CAS #:67562-39-4Molecular Formula:¹³C₁₂HCl₇OMolecular Weight:421.22Category:Standards; Isotopic Labeled Analogues;Applications:1,​2,​3,​4,​6,​7,​8-​Heptachloro-dibenzofuran-​13C12 can be used to develop detection methods of polychlorinated dibenzo-​p-​dioxins and polychlorinated dibenzofurans using gas chromatography and mass spectrometry.References:Watanabe-Ezoe, Y., et al.: Anal. Chem 82, 6519 (2010)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that […]

Chemical Name:3-Hydroxy-SulthiameSynonyms:Sultiame Metabolite 1Molecular Formula:C10H14N2O5S2.Molecular Weight:306.4To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low […]

Chemical Name:L-Leucyl-L-seryl-L-lysyl-L-leucinamideSynonyms:(S)-6-amino-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-2-((S)-2-((S)-2-amino-4-methylpentanamido)-3-hydroxypropanamido)hexanamideCAS Number:283609-79-0Molecular Formula:C₂₁H₄₂N₆O₅Molecular Weight:458.6Applications:L-Leucyl-L-seryl-L-lysyl-L-leucinamide can be useful in the study of relative contributions of core protein and solvation shell in terahertz dielectric properties of protein solutions.References:Grognot, M., et al.: J. Phys. Chem. B, 121, 9508 (2017)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that […]

Chemical Name:Hydroxy CariprazineSynonyms:N’-[trans-4-[2-[4-(2,3-dichloro-4-hydroxyphenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethyl-UreaCAS Number:1084891-95-1Molecular Formula:C₂₁H₃₂Cl₂N₄O₂Molecular Weight:443.41Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Hydroxy cariprazine is a derivative of cariprazine (C183490), an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.References:(1) Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); (2) Seneca, N. et […]