12-O-Methyl Clarithromycin-d3

Chemical Name:12-O-Methyl Clarithromycin-d3
Synonyms:6,12-Di-O-methylerythromycin-d3; 6,12-Di-O-methylerythromycin A-d3; Clarithromycin EP Impurity F-d3;
Alternate CAS #:unlabelled: 128940-83-0
Molecular Formula:C₃₉H₆₈D₃NO₁₃
Molecular Weight:765
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:Labelled analogue of 12-O-Methyl Clarithromycin, a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
References:Chen, X. et al.: Zhong. Yao., 17, 32 (2008); Yoshida, H. et al.: Jap. J. Antibiot., 53, 615 (2000); Omura, S. et al.: Yakug. Zas., 112, 593 (1992);
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