2-[[[2-Amino-4-(aminocarbonyl)-4,5-dihydro-5-oxo-1H-imidazol-4-yl]formylamino]methoxy]acetic Acid

Chemical Name:2-[[[2-Amino-4-(aminocarbonyl)-4,5-dihydro-5-oxo-1H-imidazol-4-yl]formylamino]methoxy]acetic Acid
Synonyms:COFA Acyclovir Impurity
CAS Number:1358087-85-0
Molecular Formula:C₈H₁₁N₅O₆
Molecular Weight:273.2
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-[[[2-Amino-4-(aminocarbonyl)-4,5-dihydro-5-oxo-1H-imidazol-4-yl]formylamino]methoxy]acetic Acid is an oxidation product of the antiviral drug acyclovir (A192400) and was detected in finished drinking water of a German waterworks after ozonization and subsequent activated carbon treatment.
References:Prasse, C., et al.: Environ. Sci. Technol, 46, 2169 (2012).
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